Invention Grant
- Patent Title: Curcumin analogues and uses thereof
- Patent Title (中): 姜黄素类似物及其用途
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Application No.: US12030691Application Date: 2008-02-13
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Publication No.: US07709535B2Publication Date: 2010-05-04
- Inventor: Kuo-Hsiung Lee , Li Lin , Charles C-Y Shih , Ching-Yuan Su , Junko Ishida , Hironori Ohtsu , Hui-Kang Wang , Hideji Itokawa , Chawnshang Chang
- Applicant: Kuo-Hsiung Lee , Li Lin , Charles C-Y Shih , Ching-Yuan Su , Junko Ishida , Hironori Ohtsu , Hui-Kang Wang , Hideji Itokawa , Chawnshang Chang
- Applicant Address: US NC Chapel Hill US NY Rochester US CA San Diego
- Assignee: The University of North Carolina at Chapel Hill,The University of Rochester Medical Center,Androscience Corporation
- Current Assignee: The University of North Carolina at Chapel Hill,The University of Rochester Medical Center,Androscience Corporation
- Current Assignee Address: US NC Chapel Hill US NY Rochester US CA San Diego
- Agency: Myers, Bigel, Sibley & Sajovec P.A.
- Main IPC: A01N35/00
- IPC: A01N35/00 ; C07C49/00
Abstract:
The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired.
Public/Granted literature
- US07595346B2 Curcumin analogues and uses thereof Public/Granted day:2009-09-29
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