Invention Grant
US07709617B2 Synergistic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy
失效
使用免疫刺激性寡核苷酸和/或免疫化合物与细胞因子和/或化学治疗剂或放射治疗联合使用免疫系统的协同刺激
- Patent Title: Synergistic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy
- Patent Title (中): 使用免疫刺激性寡核苷酸和/或免疫化合物与细胞因子和/或化学治疗剂或放射治疗联合使用免疫系统的协同刺激
-
Application No.: US11173983Application Date: 2005-07-01
-
Publication No.: US07709617B2Publication Date: 2010-05-04
- Inventor: Ekambar R. Kandimalla , Sudhir Agrawal
- Applicant: Ekambar R. Kandimalla , Sudhir Agrawal
- Applicant Address: US MA Cambridge
- Assignee: Idera Pharmaceuticals, Inc.
- Current Assignee: Idera Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Preti Flaherty
- Agent Wayne A. Keown
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/00 ; A61K31/7088 ; A61K31/7115
Abstract:
The invention provides optimized methods and compositions for enhancing the immune response caused by immunostimulatory compounds used for the treatment of disease such as, but not limited to, treatment of cancer, autoimmune disorders, asthma, respiratory allergies, food allergies and infectious diseases in a patient. The optimized methods according to the invention provide synergy between the therapeutic effects of immunostimulatory oligonucleotides and immunomer compounds in accordance with the invention, and the therapeutic effect of cytokine immunotherapy and/or chemotherapeutic agents and/or radiation.
Public/Granted literature
Information query
