Invention Grant
US07709629B2 siRNA targeting diacylglycerol O-acyltransferase homolog 2 (DGAT2)
有权
siRNA靶向二酰基甘油O-酰基转移酶同系物2（DGAT2）
- Patent Title: siRNA targeting diacylglycerol O-acyltransferase homolog 2 (DGAT2)
- Patent Title (中): siRNA靶向二酰基甘油O-酰基转移酶同系物2（DGAT2）
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Application No.: US11978398Application Date: 2007-10-29
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Publication No.: US07709629B2Publication Date: 2010-05-04
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Kalow & Springut, LLC
- Agent Scott D. Locke, Esq.
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/02 ; C07H21/04
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for DGAT2.
Public/Granted literature
- US20080113369A1 siRNA targeting diacylglycerol O-acyltransferase homolog 2 (DGAT2) Public/Granted day:2008-05-15
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