Invention Grant
- Patent Title: Methods for treating and preventing infectious disease
- Patent Title (中): 治疗和预防传染病的方法
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Application No.: US10306522Application Date: 2002-11-27
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Publication No.: US07713529B2Publication Date: 2010-05-11
- Inventor: Arthur M. Krieg , Dennis Klinman , Alfred D. Steinberg
- Applicant: Arthur M. Krieg , Dennis Klinman , Alfred D. Steinberg
- Applicant Address: US IA Iowa City US NY New York US DC Washington
- Assignee: University of Iowa Research Foundation,Coley Pharmaceutical Group, Inc.,The United States of America as represented by the Department of Health and Human Services
- Current Assignee: University of Iowa Research Foundation,Coley Pharmaceutical Group, Inc.,The United States of America as represented by the Department of Health and Human Services
- Current Assignee Address: US IA Iowa City US NY New York US DC Washington
- Agency: Wolf, Greenfield & Sacks, P.C.
- Agent Gregg C. Benson
- Main IPC: A61K39/00
- IPC: A61K39/00

Abstract:
Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful as a synthetic adjuvant.
Public/Granted literature
- US20030191079A1 Methods for treating and preventing infectious disease Public/Granted day:2003-10-09
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