Invention Grant
- Patent Title: Adenosine Aa2 receptor antagonists
- Patent Title (中): 腺苷Aa2受体拮抗剂
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Application No.: US11767624Application Date: 2007-06-25
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Publication No.: US07713985B2Publication Date: 2010-05-11
- Inventor: Martin C. Clasby , Samuel Chackalamannil , Andrew Stamford
- Applicant: Martin C. Clasby , Samuel Chackalamannil , Andrew Stamford
- Applicant Address: US NJ Kenilworth
- Assignee: Schering Corporation
- Current Assignee: Schering Corporation
- Current Assignee Address: US NJ Kenilworth
- Agent Krishna G. Banerjee; William Y. Lee
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505 ; C07D491/00

Abstract:
Compounds having the structural formula I or a pharmaceutically acceptable salt thereof, wherein: X1 and X2 are 1-3 substituents independently selected from the group consisting of H, alkyl, halo, —CF3, —OCF3, alkoxy, —OH and —CN; n is 0, 1 or 2; and R and R1 are H or alkyl; also disclosed is the use of the compounds in the treatment of CNS diseases such as Parkinson's disease, alone or in combination with other agents for treating CNS diseases, pharmaceutical compositions comprising them and kits comprising the components of the combinations.
Public/Granted literature
- US20080255156A1 ADENOSINE A2A RECEPTOR ANTAGONISTS Public/Granted day:2008-10-16
Information query
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