Invention Grant
- Patent Title: Cytotoxic compounds and conjugates with cleavable substrates
- Patent Title (中): 细胞毒性化合物和具有可裂解底物的缀合物
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Application No.: US11398854Application Date: 2006-04-06
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Publication No.: US07714016B2Publication Date: 2010-05-11
- Inventor: Sanjeev Gangwar , Bilal Sufi
- Applicant: Sanjeev Gangwar , Bilal Sufi
- Applicant Address: US NJ Princeton
- Assignee: Medarex, Inc.
- Current Assignee: Medarex, Inc.
- Current Assignee Address: US NJ Princeton
- Agency: Darby & Darby PC
- Main IPC: A61K31/403
- IPC: A61K31/403 ; C07D405/02
Abstract:
The present disclosure provides drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-cleavable substrate conjugates, and to methods of treatment using them.
Public/Granted literature
- US20060247295A1 Cytotoxic compounds and conjugates with cleavable substrates Public/Granted day:2006-11-02
Information query
