Invention Grant
US07714111B2 Arginine derivative wash in protein purification using affinity chromatography
有权
使用亲和色谱法进行蛋白质纯化中的精氨酸衍生物洗涤
- Patent Title: Arginine derivative wash in protein purification using affinity chromatography
- Patent Title (中): 使用亲和色谱法进行蛋白质纯化中的精氨酸衍生物洗涤
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Application No.: US11899955Application Date: 2007-09-07
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Publication No.: US07714111B2Publication Date: 2010-05-11
- Inventor: Shujun Sun , Christopher Gallo
- Applicant: Shujun Sun , Christopher Gallo
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Agent Gloria K. Szakiel; Christopher H. Chung
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/00 ; C07K1/22
Abstract:
The invention relates to methods for isolating a product and/or reducing turbidity and/or impurities from a load fluid comprising the product and one or more impurities by passing the load fluid through a medium, followed by at least one wash solution comprising an arginine derivative, and collecting the product using an elution solution. The invention further relates to a product prepared using a method as described herein.
Public/Granted literature
- US20080064860A1 Arginine derivative wash in protein purification using affinity chromatography Public/Granted day:2008-03-13
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