Invention Grant
US07714113B2 Fusion proteins of humanized g250 specific antibodies and uses thereof
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人源化g250特异性抗体的融合蛋白及其用途
- Patent Title: Fusion proteins of humanized g250 specific antibodies and uses thereof
- Patent Title (中): 人源化g250特异性抗体的融合蛋白及其用途
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Application No.: US10504389Application Date: 2003-02-12
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Publication No.: US07714113B2Publication Date: 2010-05-11
- Inventor: Christoph Renner , Andrew Scott
- Applicant: Christoph Renner , Andrew Scott
- Applicant Address: US NY New York
- Assignee: Ludwig Institute for Cancer Research
- Current Assignee: Ludwig Institute for Cancer Research
- Current Assignee Address: US NY New York
- Agency: Fulbright & Jaworski LLP
- International Application: PCT/US03/04243 WO 20030212
- International Announcement: WO03/068924 WO 20030821
- Main IPC: C12P21/08
- IPC: C12P21/08

Abstract:
Chimeric antibodies, as well as fusion proteins which comprise chimeric antibodies, are disclosed. The antibodies bind to GM-CSF, CD-30, and G250 antigen. The fusion proteins include biologically active portions of tumor necrosis factor, or full length tumor necrosis factor. Expression vectors adapted for production of the antibodies, as well as methods for manufacturing these, are also disclosed.
Public/Granted literature
- US20060045876A1 Fusion proteins of humanized g250 specific antibodies and uses thereof Public/Granted day:2006-03-02
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