Invention Grant
- Patent Title: Method of deprotection
- Patent Title (中): 脱保护方法
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Application No.: US11576625Application Date: 2005-09-23
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Publication No.: US07714115B2Publication Date: 2010-05-11
- Inventor: Julian Grigg , Nigel Osborn
- Applicant: Julian Grigg , Nigel Osborn
- Applicant Address: GB Buckinghamshire
- Assignee: GE Healthcare Limited
- Current Assignee: GE Healthcare Limited
- Current Assignee Address: GB Buckinghamshire
- Agent Craig Bohlken
- Priority: GB0422004.2 20041005
- International Application: PCT/GB2005/003692 WO 20050923
- International Announcement: WO2006/037950 WO 20060413
- Main IPC: C07H1/00
- IPC: C07H1/00
Abstract:
The invention provides a method for the synthesis of an 18F-labelled product comprising deprotected of a protected 18F-labelled compound using a deprotection agent comprising a weak acid and wherein neutralisation and buffering of the deprotected product are carried out by the addition of a neutralisation agent. The deprotected product is buffered in a pH range suitable for subsequent autoclaving and formulation into an injectable radiopharmaceutical.
Public/Granted literature
- US20080076914A1 Method of Deprotection Public/Granted day:2008-03-27
Information query
