Invention Grant
- Patent Title: Method for preparing Fmoc-based hydrolysable linkers
- Patent Title (中): 制备基于Fmoc的可水解接头的方法
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Application No.: US12215217Application Date: 2008-06-25
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Publication No.: US07714147B2Publication Date: 2010-05-11
- Inventor: Peter Turecek , Juergen Siekmann , Christian Noe , Gerhard Stoiber
- Applicant: Peter Turecek , Juergen Siekmann , Christian Noe , Gerhard Stoiber
- Applicant Address: US IL Deerfield CH Glattpark (Opfikon)
- Assignee: Baxter International Inc.,Baxter Healthcare S.A.
- Current Assignee: Baxter International Inc.,Baxter Healthcare S.A.
- Current Assignee Address: US IL Deerfield CH Glattpark (Opfikon)
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C07D207/24
- IPC: C07D207/24
Abstract:
A novel process for the production of Fmoc (9H-fluoren-9-ylmethoxycarbonyl)-based compounds is provided, wherein a protecting group for the 9-hydroxymethyl group of the fluorene ring system is utilized. These compounds are useful for the modification of protein and peptide drugs.
Public/Granted literature
- US20090005574A1 Method for preparing Fmoc-based hydrolysable linkers Public/Granted day:2009-01-01
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