Invention Grant
US07715989B2 Systems and methods for predicting oligonucleotide melting temperature (TmS)
有权
用于预测寡核苷酸融合温度（TmS）的系统和方法
- Patent Title: Systems and methods for predicting oligonucleotide melting temperature (TmS)
- Patent Title (中): 用于预测寡核苷酸融合温度（TmS）的系统和方法
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Application No.: US10176972Application Date: 2002-06-18
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Publication No.: US07715989B2Publication Date: 2010-05-11
- Inventor: Robert O. Dempcy , Alexander A. Gall , Sergey G. Lokhov , Irina A. Afonina , Michael J. Singer , Igor V. Kutyavin , Nicolaas M. J. Vermeulen
- Applicant: Robert O. Dempcy , Alexander A. Gall , Sergey G. Lokhov , Irina A. Afonina , Michael J. Singer , Karen M. Singer, legal representative , Igor V. Kutyavin , Nicolaas M. J. Vermeulen
- Applicant Address: NL
- Assignee: Elitech Holding B.V.
- Current Assignee: Elitech Holding B.V.
- Current Assignee Address: NL
- Agency: Jackson Walker L.L.P.
- Main IPC: G01N33/48
- IPC: G01N33/48
Abstract:
Software systems and methods for predicting the melting temperature (Tm) and other characteristics of oligonucleotides, including modified oligonucleotides. Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.
Public/Granted literature
- US20030235822A1 Systems and methods for predicting oligonucleotide melting temperature (TmS) Public/Granted day:2003-12-25
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