Invention Grant
US07718398B2 Promoters having a modified transcription efficiency and derived from methyltrophic yeast
有权
具有修饰的转录效率并衍生自甲基营养酵母的启动子
- Patent Title: Promoters having a modified transcription efficiency and derived from methyltrophic yeast
- Patent Title (中): 具有修饰的转录效率并衍生自甲基营养酵母的启动子
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Application No.: US10513836Application Date: 2003-05-08
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Publication No.: US07718398B2Publication Date: 2010-05-18
- Inventor: Manfred Suckow
- Applicant: Manfred Suckow
- Applicant Address: DE Dusseldorf
- Assignee: Rhein Biotech Gesellschaft fur Neue Biotechnologische Prozesse und Produkte mbH
- Current Assignee: Rhein Biotech Gesellschaft fur Neue Biotechnologische Prozesse und Produkte mbH
- Current Assignee Address: DE Dusseldorf
- Agency: Alston & Bird LLP
- Priority: DE10220894 20020510
- International Application: PCT/EP03/04844 WO 20030508
- International Announcement: WO03/095653 WO 20031120
- Main IPC: C12P21/02
- IPC: C12P21/02
Abstract:
The present invention relates to a deoxyribonucleic acid (DNA) comprising at least one promoter sequence, which is derived from a wild-type promoter of a methyltrophic yeast, whose transcription efficiency is modulated in comparison to the efficiency of the wild-type promoter by inserting or modifying a DNA binding site. The invention also relates to host cells, expression vectors, kits and methods for producing proteins while using the inventive DNA, as well as to different uses of the same and to a method for producing expression vectors.
Public/Granted literature
- US20060089492A1 Promoters having a modified transcription efficiency and derived from methyltrophic yeast Public/Granted day:2006-04-27
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