Invention Grant
US07718667B2 Fused aminopiperidines as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
有权
作为二肽基肽酶-IV抑制剂的熔融氨基哌啶用于治疗或预防糖尿病
- Patent Title: Fused aminopiperidines as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
- Patent Title (中): 作为二肽基肽酶-IV抑制剂的熔融氨基哌啶用于治疗或预防糖尿病
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Application No.: US11667415Application Date: 2005-11-22
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Publication No.: US07718667B2Publication Date: 2010-05-18
- Inventor: Scott D. Edmondson , Anthony Mastracchio , Jason M. Cox
- Applicant: Scott D. Edmondson , Anthony Mastracchio , Jason M. Cox
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Philippe L. Durette; John C. Todaro
- International Application: PCT/US2005/042429 WO 20051122
- International Announcement: WO2006/058064 WO 20060601
- Main IPC: A61K31/437
- IPC: A61K31/437 ; C07D471/02
Abstract:
The present invention is directed to novel substituted fused aminopiperidines which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DPP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Public/Granted literature
- US20080009510A1 Fused Aminopiperidine as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes Public/Granted day:2008-01-10
Information query
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