Invention Grant
- Patent Title: Nitrobenzindoles and their use in cancer therapy
- Patent Title (中): 硝基苯并吲哚及其在癌症治疗中的应用
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Application No.: US11666014Application Date: 2005-10-21
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Publication No.: US07718688B2Publication Date: 2010-05-18
- Inventor: William Alexander Denny , William Robert Wilson , Ralph James Stevenson , Moana Tercel , Graham John Atwell , Shangjin Yang , Adam Vorn Patterson , Frederik Bastlaan Pruijn
- Applicant: William Alexander Denny , William Robert Wilson , Ralph James Stevenson , Moana Tercel , Graham John Atwell , Shangjin Yang , Adam Vorn Patterson , Frederik Bastlaan Pruijn
- Applicant Address: NZ Auckland
- Assignee: Auckland Uniservices Limited
- Current Assignee: Auckland Uniservices Limited
- Current Assignee Address: NZ Auckland
- Agency: Nixon & Vanderhye
- Priority: NZ536107 20041022
- International Application: PCT/NZ2005/000278 WO 20051021
- International Announcement: WO2006/043839 WO 20060427
- Main IPC: A61K31/403
- IPC: A61K31/403 ; C07D209/60

Abstract:
The present invention relates generally to nitro-1,2-dihydro-3H-benzo[e]indoles and related analogues, to their preparation, and to their use as hypoxia-selective drugs and radiosensitizers for cancer therapy, both alone or in combination with radiation and/or other anticancer drugs.
Public/Granted literature
- US20080119442A1 Nitrobenzindoles and Their use in Cancer Therapy Public/Granted day:2008-05-22
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