Invention Grant
- Patent Title: Receptor antagonists and their methods of use
- Patent Title (中): 受体拮抗剂及其使用方法
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Application No.: US11772977Application Date: 2007-07-03
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Publication No.: US07718693B2Publication Date: 2010-05-18
- Inventor: Daryl Simon Walter
- Applicant: Daryl Simon Walter
- Applicant Address: GB Greenford, Middlesex
- Assignee: Glaxo Group Limited
- Current Assignee: Glaxo Group Limited
- Current Assignee Address: GB Greenford, Middlesex
- Agent Duke M. Fitch; Kathryn L. Sieburth; Lorraine B. Ling
- Priority: GB0613473.8 20060706; GB0622825.8 20061115; GB0705263.2 20070319; GB0711439.0 20070613
- Main IPC: A61K31/4015
- IPC: A61K31/4015 ; C07D207/04
Abstract:
The present invention relates to novel oxo-prolinamide derivatives of formula (I) which modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor and the use of such compounds or pharmaceutical compositions thereof in the treatment of disorders mediated by the P2X7 receptor, for example pain, inflammation and neurodegeneration.
Public/Granted literature
- US20080009541A1 Novel Receptor Antagonists and Their Methods of Use Public/Granted day:2008-01-10
Information query
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