A method of manufacturing super-absorbent polymer (SAP) which is powdery, insoluble in water, and able to absorb water, blood and urine with slight soluble substances. The method includes at least the following steps: mixing a monomer solution having at least 50 mol % of neutralized acrylic acid with polymerization initiators to synthesize a sticky precursor, wherein the monomer can be selected from acrylic acid, methacrylic acid, 2-acrylamido-2-methyl-propane sulfonic acid, or the mixtures thereof; mixing high hydrophilic epoxy compounds and polymerization initiators with the precursor and producing a gel via UV cross-linking; drying the gel at temperature of 100 to 250° C. to obtain a polymer; grinding and screening the polymer into constant particle size; coating the polymer with surface cross-linking agents; heating the polymer at temperature of 80 to 230° C.; and adding powdery inert inorganic salts into the polymer.