Invention Grant
- Patent Title: Process for the preparation of caprolactam CGRP antagonist
- Patent Title (中): 制备己内酰胺CGRP拮抗剂的方法
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Application No.: US12226113Application Date: 2007-04-06
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Publication No.: US07718796B2Publication Date: 2010-05-18
- Inventor: Michael Palucki , Ian Davies , Dietrich Steinhuebel , Jonathan Rosen
- Applicant: Michael Palucki , Ian Davies , Dietrich Steinhuebel , Jonathan Rosen
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Gerard Devlin; Raynard Yurd
- International Application: PCT/US2007/008700 WO 20070406
- International Announcement: WO2007/120589 WO 20071025
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D471/04

Abstract:
An efficient syntheses for the preparation of (3R,6S)-3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one.
Public/Granted literature
- US20090124799A1 Process for the preparation of Caprolactam Cgrp Antagonist Public/Granted day:2009-05-14
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