Invention Grant
- Patent Title: Substituted melanocortin receptor-specific piperazine compounds
- Patent Title (中): 取代的黑皮质素受体特异性哌嗪化合物
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Application No.: US11099814Application Date: 2005-04-05
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Publication No.: US07718802B2Publication Date: 2010-05-18
- Inventor: Shubh D. Sharma , Yi-Qun Shi , Ramesh Rajpurohit , Zhijun Wu
- Applicant: Shubh D. Sharma , Yi-Qun Shi , Ramesh Rajpurohit , Zhijun Wu
- Applicant Address: US NJ Cranbury
- Assignee: Palatin Technologies, Inc.
- Current Assignee: Palatin Technologies, Inc.
- Current Assignee Address: US NJ Cranbury
- Agent Stephen A. Slusher
- Main IPC: C07D241/04
- IPC: C07D241/04 ; C07D403/06 ; C07D295/023

Abstract:
Melanocortin receptor-specific compounds of the general formulas and pharmaceutically acceptable salts thereof, where J is a substituted or unsubstituted monocyclic or bicyclic ring structure, L is a linker, W is a heteroatom unit with at least one cationic center, hydrogen bond donor or hydrogen bond acceptor, Q includes a substituted or unsubstituted aromatic carbocyclic ring, R6, R7, y and z are as defined in the specification, and the carbon atom marked with an asterisk can have any stereochemical configuration, and optionally with one or two additional ring substituents as defined, which compounds bind to one or more melanocortin receptors and are optionally an agonist, a partial agonist, an antagonist, an inverse agonist or an antagonist of an inverse agonist, and may be employed for treatment of one or more melanocortin receptor-associated conditions or disorders, and methods for the use of the compounds of the invention.
Public/Granted literature
- US20050176728A1 Substituted melanocortin receptor-specific piperazine compounds Public/Granted day:2005-08-11
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