Invention Grant
- Patent Title: Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids
- Patent Title (中): 用于检测生理液体中单糖水溶液的四元氮杂环化合物
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Application No.: US11318663Application Date: 2005-12-27
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Publication No.: US07718804B2Publication Date: 2010-05-18
- Inventor: Chris D. Geddes , Ramachandram Badugu , Joseph R. Lakowicz
- Applicant: Chris D. Geddes , Ramachandram Badugu , Joseph R. Lakowicz
- Applicant Address: US MD Baltimore
- Assignee: University of Maryland Biotechnology Institute
- Current Assignee: University of Maryland Biotechnology Institute
- Current Assignee Address: US MD Baltimore
- Agency: Moore & Van Allen, PLLC
- Agent Marianne Fuierer
- Main IPC: C07D215/38
- IPC: C07D215/38
Abstract:
Quaternary nitrogen heterocyclic boronic acid-containing compounds are described, which are sensitive to glucose and fructose, as well as a variety of other physiologically important analytes, such as aqueous chloride and iodide, and a method of using the compounds. Also disclosed is a contact lens doped with the quaternary nitrogen heterocyclic boronic acid-containing compound, and a method of using the doped contact lens to measure the concentration of analyte in tears under physiological conditions.
Public/Granted literature
- US20070020182A1 Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids Public/Granted day:2007-01-25
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