Invention Grant
US07718809B2 Chromane substituted benzimidazole derivatives as acid pump antagonists
有权
色烷取代的苯并咪唑衍生物作为酸泵拮抗剂
- Patent Title: Chromane substituted benzimidazole derivatives as acid pump antagonists
- Patent Title (中): 色烷取代的苯并咪唑衍生物作为酸泵拮抗剂
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Application No.: US11916671Application Date: 2006-06-02
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Publication No.: US07718809B2Publication Date: 2010-05-18
- Inventor: Hiroki Koike , Sachiko Sakakibara
- Applicant: Hiroki Koike , Sachiko Sakakibara
- Applicant Address: JP Aichi-ken
- Assignee: RaQualia Pharma Inc.
- Current Assignee: RaQualia Pharma Inc.
- Current Assignee Address: JP Aichi-ken
- Agency: Scully, Scott, Murphy & Presser, P.C.
- International Application: PCT/IB2006/001567 WO 20060602
- International Announcement: WO2006/134460 WO 20061221
- Main IPC: A61K31/4184
- IPC: A61K31/4184 ; C07D405/12

Abstract:
This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, B, X, R1, R2, R3, R4, R5 and R6, R7, R8 and R9 are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by acid pump antagonistic activity such as, but not limited to, as gastrointestinal disease, gastroesophageal disease, gastroesophageal reflux disease (GERD), peptic ulcer, gastric ulcer, duodenal ulcer, NSAID-induced ulcers, gastritis, infection of Helicobacter pylori, dyspepsia, functional dyspepsia, Zollinger-Ellison syndrome, non-erosive reflux disease (NERD), visceral pain, heartburn, nausea, esophagitis, dysphagia, hypersalivation, airway disorders or asthma.
Public/Granted literature
- US20080214519A1 Chromane Substituted Benzimidazole Derivatives as Acid Pump Antagonists Public/Granted day:2008-09-04
Information query
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