According to one embodiment of the invention, a technique is provided for facilitating the relocation of data from a source page to a destination page in a computing system in which I/O devices may conduct DVMA transactions via an IOMMU. Before the relocation, it is determined whether any devices potentially are accessing the source page. If it is determined that a device potentially is accessing the source page, then the IOMMU's device driver (“bus nexus”) “suspends” the bus. The bus nexus allows any pending memory transactions to finish. While the bus is suspended, the kernel moves the contents of the source page to the destination page. After the kernel has moved the contents, the IOMMU's TLB is updated so that the virtual address that was mapped to the source page's physical address is mapped to the destination page's physical address. The bus nexus “unsuspends” the bus.