Invention Grant
US07727529B2 Human monoclonal antibody Fab fragments directed against HCV E2 glycoprotein and endowed with in vitro neutralizing activity
有权
针对HCV E2糖蛋白的人单克隆抗体Fab片段，具有体外中和活性
- Patent Title: Human monoclonal antibody Fab fragments directed against HCV E2 glycoprotein and endowed with in vitro neutralizing activity
- Patent Title (中): 针对HCV E2糖蛋白的人单克隆抗体Fab片段，具有体外中和活性
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Application No.: US12128344Application Date: 2008-05-28
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Publication No.: US07727529B2Publication Date: 2010-06-01
- Inventor: Roberto Burioni
- Applicant: Roberto Burioni
- Applicant Address: IT San Marion
- Assignee: General Antibodies and Biotechnologies S.R.L
- Current Assignee: General Antibodies and Biotechnologies S.R.L
- Current Assignee Address: IT San Marion
- Agency: Law Offices of Albert Wai-Kit Chan, PLLC
- Priority: ITRM2002A0049 20020130
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/42 ; C07K16/00 ; C12P21/08
Abstract:
The invention refers to a human antibody, or its functional fragments, directed against the HCV E2 glycoprotein, able to have a neutralizing activity in vivo; a composition for anti-HCV therapy comprising in a therapeutically effective amount the antibody; a composition for topical use in gel, creme, ointment and ovule formulations; the use of the antibody for validating anti-HCV vaccines.
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