Invention Grant
US07727761B2 Vascular endothelial growth factor C (VEGF-C) protein and gene, mutants thereof, and uses thereof
失效
血管内皮生长因子C（VEGF-C）蛋白和基因，突变体及其用途
- Patent Title: Vascular endothelial growth factor C (VEGF-C) protein and gene, mutants thereof, and uses thereof
- Patent Title (中): 血管内皮生长因子C（VEGF-C）蛋白和基因，突变体及其用途
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Application No.: US10792480Application Date: 2004-03-03
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Publication No.: US07727761B2Publication Date: 2010-06-01
- Inventor: Kari Alitalo , Vladimir Joukov
- Applicant: Kari Alitalo , Vladimir Joukov
- Applicant Address: AU Toorak
- Assignee: Vegenics Limited
- Current Assignee: Vegenics Limited
- Current Assignee Address: AU Toorak
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02 ; A01N43/04 ; A01K31/70
Abstract:
Provided are purified and isolated VEGF-C polypeptides capable of binding to at least one of KDR receptor tyrosine kinase (VEGFR-2) and Flt4 receptor tyrosine kinase (VEGFR-3); analogs of such peptides that have VEGF-C-like or VEGF-like biological activities or that are VEGF or VEGF-C inhibitors; polynucleotides encoding the polypeptides; vectors and host cells that embody the polynucleotides; pharmaceutical compositions and diagnostic reagents comprising the polypeptides; and methods of making and using the polypeptides.
Public/Granted literature
- US20040147448A1 Vascular endothelial growth factor C (VEGF-C) protein and gene, mutants thereof, and uses thereof Public/Granted day:2004-07-29
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