Invention Grant
- Patent Title: N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives
- Patent Title (中): N，N'-取代-1,3-二氨基-2-羟基丙烷衍生物
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Application No.: US11636903Application Date: 2006-12-11
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Publication No.: US07727997B2Publication Date: 2010-06-01
- Inventor: Varghese John , Michel Maillard , Barbara Jagodzinska , James Beck , Andrea Gailunas , John Freskos , John Mickelson , Lakshman Samala , Jennifer Sealey , Ruth Tenbrink , Larry Fang , Roy Hom
- Applicant: Varghese John , Michel Maillard , Barbara Jagodzinska , James Beck , Andrea Gailunas , John Freskos , John Mickelson , Lakshman Samala , Jennifer Sealey , Ruth Tenbrink , Larry Fang , Roy Hom
- Applicant Address: US CA So. San Francisco
- Assignee: Elan Pharmaceuticals, Inc.
- Current Assignee: Elan Pharmaceuticals, Inc.
- Current Assignee Address: US CA So. San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: A61K31/133
- IPC: A61K31/133 ; C07D217/00
Abstract:
Disclosed are compounds of the formula wherein the variables RN, RC, R1, R25, R2, and R3 are as defined herein. These compounds have activity as inhibitors of beta-secretase and are therefore useful in treating a variety of disorders such as Alzheimer's Disease.
Public/Granted literature
- US20070213316A1 N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives Public/Granted day:2007-09-13
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