Invention Grant
US07728010B2 Substituted benz-azoles and methods of their use as inhibitors of Raf kinase
失效
取代的苯并唑及其用作Raf激酶抑制剂的方法
- Patent Title: Substituted benz-azoles and methods of their use as inhibitors of Raf kinase
- Patent Title (中): 取代的苯并唑及其用作Raf激酶抑制剂的方法
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Application No.: US11282939Application Date: 2005-11-18
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Publication No.: US07728010B2Publication Date: 2010-06-01
- Inventor: Payman Amiri , Wendy Fantl , Teresa Hansen , Barry Haskell Levine , Christopher McBride , Daniel J Poon , Savithri Ramurthy , Paul A Renhowe , Cynthia M Shafer , Sharadha Subramanian , Leonard Sung
- Applicant: Payman Amiri , Wendy Fantl , Teresa Hansen , Barry Haskell Levine , Christopher McBride , Daniel J Poon , Savithri Ramurthy , Paul A Renhowe , Cynthia M Shafer , Sharadha Subramanian , Leonard Sung
- Applicant Address: US CA Emeryville
- Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee Address: US CA Emeryville
- Agency: Christensen O'Connor Johnson Kindness PLLC
- Agent George Dohmann
- Main IPC: A61K31/423
- IPC: A61K31/423 ; A61K31/4439 ; C07D263/58 ; C07D413/12
Abstract:
New substituted benz-azole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
Public/Granted literature
- US20070299039A1 Substituted benz-azoles and methods of their use as inhibitors of Raf kinase Public/Granted day:2007-12-27
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