Invention Grant
US07728029B2 Adamantyl-pyrazole carboxamides as inhibitors of 11β-hdroxysteroid dehydrogenase
有权
金刚烷基 - 吡唑甲酰胺作为11＆amp; - 类固醇脱氢酶的抑制剂
- Patent Title: Adamantyl-pyrazole carboxamides as inhibitors of 11β-hdroxysteroid dehydrogenase
- Patent Title (中): 金刚烷基 - 吡唑甲酰胺作为11＆amp; - 类固醇脱氢酶的抑制剂
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Application No.: US11717996Application Date: 2007-03-14
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Publication No.: US07728029B2Publication Date: 2010-06-01
- Inventor: Kevin William Anderson , Nader Fotouhi , Paul Gillespie , Robert Alan Goodnow, Jr. , Kevin Richard Guertin , Nancy-Ellen Haynes , Michael Paul Myers , Sherrie Lynn Pietranico-Cole , Lida Qi , Pamela Loreen Rossman , Nathan Robert Scott , Kshitij Chhabilbhai Thakkar , Jefferson Wright Tilley , Qiang Zhang
- Applicant: Kevin William Anderson , Nader Fotouhi , Paul Gillespie , Robert Alan Goodnow, Jr. , Kevin Richard Guertin , Nancy-Ellen Haynes , Michael Paul Myers , Sherrie Lynn Pietranico-Cole , Lida Qi , Pamela Loreen Rossman , Nathan Robert Scott , Kshitij Chhabilbhai Thakkar , Jefferson Wright Tilley , Qiang Zhang
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Dennis P. Tramaloni; Samuel H. Megerditchian
- Main IPC: A61K31/4155
- IPC: A61K31/4155 ; A61K31/415 ; A61K31/454 ; A61K31/5377 ; C07D231/14 ; C07D401/04 ; C07D413/04 ; C07D403/04
Abstract:
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
Public/Granted literature
- US20070225280A1 Adamantyl-pyrazole carboxamides as inhibitors of 11B-hydroxysteroid dehydrogenase Public/Granted day:2007-09-27
Information query
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