Invention Grant
US07728119B2 Nucleotide primer set and nucleotide probe for detecting genotype of methylene tetrahydrofolate reductase (MTHFR)
失效
用于检测亚甲基四氢叶酸还原酶（MTHFR）基因型的核苷酸引物组和核苷酸探针
- Patent Title: Nucleotide primer set and nucleotide probe for detecting genotype of methylene tetrahydrofolate reductase (MTHFR)
- Patent Title (中): 用于检测亚甲基四氢叶酸还原酶（MTHFR）基因型的核苷酸引物组和核苷酸探针
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Application No.: US12015645Application Date: 2008-01-17
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Publication No.: US07728119B2Publication Date: 2010-06-01
- Inventor: Naoko Nakamura , Keiko Ito , Masayoshi Takahashi , Koji Hashimoto , Nobuhiro Gemma
- Applicant: Naoko Nakamura , Keiko Ito , Masayoshi Takahashi , Koji Hashimoto , Nobuhiro Gemma
- Applicant Address: JP Tokyo
- Assignee: Kabushiki Kaisha Toshiba
- Current Assignee: Kabushiki Kaisha Toshiba
- Current Assignee Address: JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2007-084288 20070328
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C12Q1/68
Abstract:
There is provided is a nucleotide primer set for LAMP amplification used for detecting genotypes of single-nucleotide polymorphisms C677T and A1298C of an MTHFR gene. There is also provided a nucleotide probe for detecting an amplification product amplified by the primer set according to the present invention. There is also provided a method of detecting the genotypes of the single-nucleotide polymorphisms C677T and A1298C in the MTHFR gene, by using the primer set according to the present invention.
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