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US07728136B2 Method for the preparation of aryl piperazinyl-heterocyclic compounds 失效
芳基哌嗪基杂环化合物的制备方法

Method for the preparation of aryl piperazinyl-heterocyclic compounds
Abstract:
A novel method for preparing a compound of formula I which comprises of coupling the piperazine derivative of formula II with alkyl halide containing compound of the formula III by heating in solvent free conditions or, optionally, in a minimum quantity of non-aqueous suspending liquid, in presence of a catalyst and a neutralizing agent to neutralize the hydrohalic acid.
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