A method includes advancing a distal end of a tubular nasopharyngeal airway device through a nostril opening and into a nasal passageway of a patient, the nasopharyngeal airway device having a proximal end that is larger than the nostril opening. At least a terminal tip of a resiliently flexible elongated locking protrusion that projects from the proximal end of the nasopharyngeal airway device is inserted into the same nostril opening in which the nasopharyngeal airway device is disposed so that the locking protrusion biases against the lining of the nasal passageway, thereby securing the nasopharyngeal airway device within the nasal passageway.