Invention Grant
- Patent Title: Metal complexes based on tetrathiol ligands and their use in nuclear medical diagnostics and endoradionuclide therapy and method for producing said metal complexes
- Patent Title (中): 基于四硫醇配体的金属络合物及其在核医学诊断和内消旋放射治疗中的应用及其制备方法
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Application No.: US11579575Application Date: 2005-04-28
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Publication No.: US07731936B2Publication Date: 2010-06-08
- Inventor: Tobias Heinrich , Bernd Johannsen , Hans-Juergen Pietzsch , Sepp Seifert , Hartmut Spies
- Applicant: Tobias Heinrich , Bernd Johannsen , Hans-Juergen Pietzsch , Sepp Seifert , Hartmut Spies
- Applicant Address: DE Dresden
- Assignee: Forschungszentrum Rossendorf E,V
- Current Assignee: Forschungszentrum Rossendorf E,V
- Current Assignee Address: DE Dresden
- Agency: Jordan and Hamburg LLP
- Priority: DE102004022461 20040506
- International Application: PCT/DE2005/000868 WO 20050428
- International Announcement: WO2005/108330 WO 20051117
- Main IPC: A61K51/00
- IPC: A61K51/00 ; C07F13/00
Abstract:
Provided are radiolytically and metabolically stable metal complexes based on tetrathiol ligands useful for nuclear medical diagnostics and in endoradionuclide therapy. Methods for their preparation are also provided. The complexes can have a central ligand, Y, that can be 99mTcO, 186ReO, 188ReO, 99mTcN, 186ReN or 188ReN.
Public/Granted literature
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