Invention Grant
- Patent Title: Variants of the major allergen Phl p 1 from timothy grass
- Patent Title (中): 主要变应原的变体Phl p 1从蒂莫西草
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Application No.: US10525000Application Date: 2003-07-31
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Publication No.: US07731970B2Publication Date: 2010-06-08
- Inventor: Roland Suck , Helmut Fiebig , Oliver Cromwell
- Applicant: Roland Suck , Helmut Fiebig , Oliver Cromwell
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano, Branigan, P.C.
- Priority: EP02018157 20020819
- International Application: PCT/EP03/08471 WO 20030731
- International Announcement: WO2004/022588 WO 20040318
- Main IPC: A01N37/18
- IPC: A01N37/18 ; A61K38/00 ; A61K39/00 ; A61K39/35 ; A61K39/36 ; C07K17/00 ; C07K2/00 ; C07K4/00 ; C07K5/00 ; C07K7/00 ; C07K14/00 ; C07K16/00
Abstract:
The invention relates to pharmaceutically important variants of the major allergen Phl p 1 from timothy grass, characterized in that a preparation, hitherto not possible, of monomeric molecules which are soluble and stable in physiological media can be carried out with the aid of prokaryotic expression systems and subsequent purification thereof.
Public/Granted literature
- US20060251682A1 Variants of the major allergen phl p 1 from timothy grass Public/Granted day:2006-11-09
Information query
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