Invention Grant
US07732203B2 Method for transdifferentiating mesenchymal stem cells into neuronal cells
有权
将间充质干细胞转分化为神经元细胞的方法
- Patent Title: Method for transdifferentiating mesenchymal stem cells into neuronal cells
- Patent Title (中): 将间充质干细胞转分化为神经元细胞的方法
-
Application No.: US10525679Application Date: 2003-08-14
-
Publication No.: US07732203B2Publication Date: 2010-06-08
- Inventor: Hae-Young Suh , Sung-Soo Kim , Ji-Won Kim , Young-Don Lee , Seung-Cheol Ahn
- Applicant: Hae-Young Suh , Sung-Soo Kim , Ji-Won Kim , Young-Don Lee , Seung-Cheol Ahn
- Applicant Address: KR
- Assignee: Ajoll University Industry Cooperation Foundation
- Current Assignee: Ajoll University Industry Cooperation Foundation
- Current Assignee Address: KR
- Agency: Baker & Hostetler, LLP
- Priority: KR10-2002-0048683 20020817
- International Application: PCT/KR03/01641 WO 20030814
- International Announcement: WO2004/016779 WO 20040226
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/00 ; C12N5/08 ; C12N5/00 ; C12N5/02
Abstract:
This inventive discloses a method for transdifferentiating mesenchymal stem cells into neuronal cells, which comprises increasing the level of a basic helix-loop-helix (bHLH) transcription factor in the mesenchymal stem cells, said cells being useful in cell therapy or gene therapy for treating brain neurological diseases such as Parkinson's disease, Alzheimer disease, Hungtington's disease, amyotrophic lateral sclerosis, cerebral paralysis and brain ischemia; and spine disfunction caused by a traumatic injury.
Public/Granted literature
- US20060099190A1 Method for transdifferentiating mesenchymal stem cells into neuronal cells Public/Granted day:2006-05-11
Information query
