Invention Grant
US07732417B2 Methods and compositions for RNA interference using recombinant Dicer and Argonaut
有权
使用重组Dicer和Argonaut进行RNA干扰的方法和组合物
- Patent Title: Methods and compositions for RNA interference using recombinant Dicer and Argonaut
- Patent Title (中): 使用重组Dicer和Argonaut进行RNA干扰的方法和组合物
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Application No.: US09858862Application Date: 2001-05-16
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Publication No.: US07732417B2Publication Date: 2010-06-08
- Inventor: David Beach , Emily Bernstein , Amy Caudy , Scott Hammond , Gregory Hannon
- Applicant: David Beach , Emily Bernstein , Amy Caudy , Scott Hammond , Gregory Hannon
- Applicant Address: US NY Cold Spring Harbor
- Assignee: Cold Spring Harbor Laboratory
- Current Assignee: Cold Spring Harbor Laboratory
- Current Assignee Address: US NY Cold Spring Harbor
- Agency: Wilmer Cutler Pickering Hale and Dorr LLP
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/04
Abstract:
The present invention provides methods for attenuating gene expression in a cell using gene-targeted double stranded RNA (dsRNA). The dsRNA contains a nucleotide sequence that hybridizes under physiologic conditions of the cell to the nucleotide sequence of at least a portion of the gene to be inhibited (the “target” gene).
Public/Granted literature
- US20040018999A1 Methods and compositions for RNA interference Public/Granted day:2004-01-29
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