Invention Grant
- Patent Title: CGRP receptor antagonists
- Patent Title (中): CGRP受体拮抗剂
-
Application No.: US11665520Application Date: 2005-10-12
-
Publication No.: US07732438B2Publication Date: 2010-06-08
- Inventor: Daniel V. Paone , Anthony W. Shaw , Craig M. Potteiger
- Applicant: Daniel V. Paone , Anthony W. Shaw , Craig M. Potteiger
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Gerard Devlin; Raynard Yuro
- International Application: PCT/US2005/036659 WO 20051012
- International Announcement: WO2006/044449 WO 20060427
- Main IPC: C07D401/00
- IPC: C07D401/00 ; C07D487/00 ; A61K31/55 ; A61P25/00
Abstract:
Compounds of Formula (I) and Formula (II) (where variables R1, R2, R4, A, B, W, X, Y and Z are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Public/Granted literature
- US20070287697A1 Cgrp Receptor Antagonists Public/Granted day:2007-12-13
Information query
