Invention Grant
US07732453B2 Pyrido[2,3-B] pyrazin-3(4H)-ones for use as stearoyl CoA desaturase inhibitors
失效
用作硬脂酰辅酶A去饱和酶抑制剂的吡啶并[2,3-B]吡嗪-3（4H） - 酮
![Pyrido[2,3-B] pyrazin-3(4H)-ones for use as stearoyl CoA desaturase inhibitors](/docs/US/2010-06-08/US07732453B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrido[2,3-B] pyrazin-3(4H)-ones for use as stearoyl CoA desaturase inhibitors
- Patent Title (中): 用作硬脂酰辅酶A去饱和酶抑制剂的吡啶并[2,3-B]吡嗪-3（4H） - 酮
-
Application No.: US11868386Application Date: 2007-10-05
-
Publication No.: US07732453B2Publication Date: 2010-06-08
- Inventor: Dmitry Koltun , Jeff Zablocki , Eric Parkhill , Andrey Glushkov , Natalya Vasilevich , Timur Zilbershtein , Alexey Ivanov
- Applicant: Dmitry Koltun , Jeff Zablocki , Eric Parkhill , Andrey Glushkov , Natalya Vasilevich , Timur Zilbershtein , Alexey Ivanov
- Applicant Address: US CA Foster City
- Assignee: Gilead Palo Alto, Inc.
- Current Assignee: Gilead Palo Alto, Inc.
- Current Assignee Address: US CA Foster City
- Agent J. Elin Hartrum
- Main IPC: A61K31/4965
- IPC: A61K31/4965
![Pyrido[2,3-B] pyrazin-3(4H)-ones for use as stearoyl CoA desaturase inhibitors](/abs-image/US/2010/06/08/US07732453B2/abs.jpg.150x150.jpg)
Abstract:
The present invention discloses pyrido[2,3-B]pyrazin-3(4h)-ones for use as inhibitors of stearoyl-CoA desaturase. The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, oily skin conditions, metabolic syndrome, and the like.
Public/Granted literature
- US20080139570A1 BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS FOR USE AS STEAROYL CoA DESATURASE INHIBITORS Public/Granted day:2008-06-12
Information query
