Invention Grant
US07732471B2 6-oxazol-4-ylmetholmethoxy-alko-alkoxymethyl substituted benzoic acid derivatives forming peroxisome proliferator—activated receptor (PPAR) ligands, process for their preparation and methods of use thereof
有权
形成过氧化物酶体增殖物激活受体（PPAR）配体的6-恶唑-4-基甲氧基 - 烷基 - 烷氧基甲基取代的苯甲酸衍生物及其制备方法及其使用方法
- Patent Title: 6-oxazol-4-ylmetholmethoxy-alko-alkoxymethyl substituted benzoic acid derivatives forming peroxisome proliferator—activated receptor (PPAR) ligands, process for their preparation and methods of use thereof
- Patent Title (中): 形成过氧化物酶体增殖物激活受体（PPAR）配体的6-恶唑-4-基甲氧基 - 烷基 - 烷氧基甲基取代的苯甲酸衍生物及其制备方法及其使用方法
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Application No.: US11949833Application Date: 2007-12-04
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Publication No.: US07732471B2Publication Date: 2010-06-08
- Inventor: Christian Stapper , Heiner Glombik , Eugen Falk , Stefanie Keil , Hans-Ludwig Schaefer , Wolfgang Wendler , Stephanie Hachtel
- Applicant: Christian Stapper , Heiner Glombik , Eugen Falk , Stefanie Keil , Hans-Ludwig Schaefer , Wolfgang Wendler , Stephanie Hachtel
- Applicant Address: FR Paris
- Assignee: Sanofi-Aventis
- Current Assignee: Sanofi-Aventis
- Current Assignee Address: FR Paris
- Agent Jiang Lin
- Priority: DE102005029382 20050624
- Main IPC: A61K31/421
- IPC: A61K31/421 ; C07D263/32 ; A61P3/08
Abstract:
The present invention comprises compounds and compositions for the treatment of metabolic disorders and more particularly, those insulin-related metabolic disorders of the blood such as hyperlipidemia, diabetes, insulin-resistance and the like comprising acetic acid derivatives with cyclohexylmethoxy substituents and their salts. Known as peroxisome proliferator-activated receptor (PPAR) agonists/antagonists, the invention relates to compounds of formula I wherein R1-R6 are further defined herein.
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