Invention Grant
US07736647B2 Anti-CD71 monoclonal antibodies and uses thereof for treating malignant tumor cells
失效
抗CD71单克隆抗体及其用于治疗恶性肿瘤细胞的用途
- Patent Title: Anti-CD71 monoclonal antibodies and uses thereof for treating malignant tumor cells
- Patent Title (中): 抗CD71单克隆抗体及其用于治疗恶性肿瘤细胞的用途
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Application No.: US11154262Application Date: 2005-06-15
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Publication No.: US07736647B2Publication Date: 2010-06-15
- Inventor: Laurence Boumsell , Armand Bensussan , Jean Kadouche
- Applicant: Laurence Boumsell , Armand Bensussan , Jean Kadouche
- Applicant Address: FR Paris FR Paris
- Assignee: Monoclonal Antibodies Therapeutics,Institut National de la Sante et de la Recherche Medicale (Inserm)
- Current Assignee: Monoclonal Antibodies Therapeutics,Institut National de la Sante et de la Recherche Medicale (Inserm)
- Current Assignee Address: FR Paris FR Paris
- Agency: Lahive & Cockfield, LLP
- Agent Megan E. Williams, Esq.
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K51/00 ; A61K39/395 ; A61K9/127 ; C07K1/00 ; C07K17/00
Abstract:
The present invention provides novel anti-CD71 monoclonal antibodies, in particular mouse-human chimeric anti-CD71 monoclonal antibodies, advantageously associated to effector cells for triggering ADCC mechanisms. Anti-CD71 antibodies, as well as pharmaceutical compositions containing them, are useful for inhibiting proliferation and/or killing malignant tumor cells, especially metastatic cutaneous and uveal melanoma cells.
Public/Granted literature
- US20060286030A1 Anti-CD71 monoclonal antibodies and uses thereof for treating malignant tumor cells Public/Granted day:2006-12-21
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