Invention Grant
- Patent Title: Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs
- Patent Title (中): 非甾体抗炎药的硫化氢衍生物
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Application No.: US11779849Application Date: 2007-07-18
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Publication No.: US07741359B2Publication Date: 2010-06-22
- Inventor: John Wallace , Giuseppe Cirino , Vincenzo Santagada , Giuseppe Caliendo
- Applicant: John Wallace , Giuseppe Cirino , Vincenzo Santagada , Giuseppe Caliendo
- Applicant Address: CA Cochrane
- Assignee: Antibe Therapeutics Inc.
- Current Assignee: Antibe Therapeutics Inc.
- Current Assignee Address: CA Cochrane
- Agency: Bennett Jones LLP
- Main IPC: C07C331/28
- IPC: C07C331/28 ; C07D333/34 ; C07D409/12 ; A61K31/26 ; A61K31/385 ; A61K31/405 ; A61P29/00 ; C07D209/28

Abstract:
The present invention relates to derivatives of non-steroidal anti-inflammatory drugs (NSAIDs) having improved anti-inflammatory properties useful in the treatment of inflammation, pain and fever. More particularly, NSAIDs are derivatized with a hydrogen sulfide (H2S) releasing moiety to produce novel anti-inflammatory compounds having reduced side effects.
Public/Granted literature
- US20080004245A1 HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS Public/Granted day:2008-01-03
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