Invention Grant
US07745604B2 Upstream control elements of the proopiomelanocortin gene and their use
有权
proopiomelanocortin基因的上游控制元件及其用途
- Patent Title: Upstream control elements of the proopiomelanocortin gene and their use
- Patent Title (中): proopiomelanocortin基因的上游控制元件及其用途
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Application No.: US11503426Application Date: 2006-08-10
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Publication No.: US07745604B2Publication Date: 2010-06-29
- Inventor: Malcolm J. Low , Marcelo Rubinstein , Flavio Silva Junqueira de Souza
- Applicant: Malcolm J. Low , Marcelo Rubinstein , Flavio Silva Junqueira de Souza
- Applicant Address: US OR Portland
- Assignee: Oregon Health & Science University
- Current Assignee: Oregon Health & Science University
- Current Assignee Address: US OR Portland
- Agency: Klarquist Sparkman, LLP
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/00 ; C12N5/00

Abstract:
The nucleic acid sequence of the POMC enhancer is disclosed herein. Sequences from the human, rat, rabbit, hamster, mouse, and cow POMC enhancer are disclosed. Hybrid transgenes, comprising a POMC transcriptional control element operably linked to a nucleic acid sequence encoding a marker are also enclosed. In addition, transgenic mice carrying a hybrid transgene including a POMC control element operably linked to a marker are disclosed herein.
Public/Granted literature
- US20070059797A1 Upstream control elements of the proopiomelanocortin gene and their use Public/Granted day:2007-03-15
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