Described herein is apparel that protects a wearer from an undesirable agent. The apparel employs a transition portal to assist doffing and to reduce the risk of cross-contamination during doffing. The transition portal attaches to the apparel proximate to one end of an aperture, which provides an exit for the protective apparel. When doffing, the transition portal extends away from the person, who exits the aperture. The transition portal is then pulled over the body along with any attached portions of the protective apparel. This turns the transition portal—and attached parts of the apparel—inside-out. After doffing, most portions of protective apparel are either a) inside-out, or b) contained within the inside-out transition portal and/or apparel. As a result, undesirable agents—that were initially on the outside of the apparel—are now inside the inside-out transition portal and apparel. In one embodiment, the transition portal is carried internal to the apparel so that surfaces of the portal are not exposed to the external environment and undesirable agent. After doffing, the transition portal may also be used as a large ‘garbage bag’ into which the apparel is placed for disposal.