A droplet ejection apparatus includes a plurality of tanks, a plurality of sub-tanks, a replenishment amount detector, a liquid replenisher and a recording head. Each of the plurality of tanks is capable of storing a different kind of basic liquid. The plurality of sub-tanks includes a first sub-tank that includes a mixed liquid of two or more of the different kinds of the basic liquids from the plurality of tanks. The replenishment amount detector detects amount of each of the different kinds of the basic liquids to be transferred to the first sub-tank. The liquid replenisher transfers the basic liquids stored in the tanks into the sub-tanks until a predetermined amount for each of the basic liquids is detected by the replenishment amount detector. The recording head ejects the liquids supplied from the sub-tanks in a form of droplets.