Invention Grant
- Patent Title: Method of forming a tablet
- Patent Title (中): 形成片剂的方法
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Application No.: US11906303Application Date: 2007-10-01
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Publication No.: US07749537B2Publication Date: 2010-07-06
- Inventor: Michael Hite , Cathy Federici , Alan Brunelle , Stephen Turner
- Applicant: Michael Hite , Cathy Federici , Alan Brunelle , Stephen Turner
- Applicant Address: US WA Bellevue
- Assignee: SCOLR Pharma, Inc.
- Current Assignee: SCOLR Pharma, Inc.
- Current Assignee Address: US WA Bellevue
- Agency: RatnerPrestia
- Main IPC: A61K9/20
- IPC: A61K9/20 ; A61K31/192

Abstract:
A method of forming a tablet includes the steps of pre-blending an active pharmaceutical ingredient susceptible to tackiness and a blending additive with a first mixing effort to form a pre-blend mixture, wherein the first mixing effort and a second mixing effort, resulting from mixing at least one excipient with the pre-blend mixture, form a blend suitable for direct compression and compressing the blend to form the tablet. One way of achieving the first mixing effort is to pre-blend for an extended period of time. The method allows for directly compressing the blend without the need for a granulation step or roller compression. One such active pharmaceutical ingredient susceptible to tackiness is ibuprofen.
Public/Granted literature
- US20080131507A1 Method of forming a tablet Public/Granted day:2008-06-05
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