Invention Grant
- Patent Title: Heterotricyclic metalloprotease inhibitors
- Patent Title (中): 异环金属蛋白酶抑制剂
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Application No.: US11986603Application Date: 2007-11-20
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Publication No.: US07749996B2Publication Date: 2010-07-06
- Inventor: Christian Gege , Carine Chevrier , Matthias Schneider , Harald Bluhm , Matthias Hochgürtel , Hongbo Deng , Brian M. Gallagher, Jr. , Irving Sucholeiki , Arthur Taveras
- Applicant: Christian Gege , Carine Chevrier , Matthias Schneider , Harald Bluhm , Matthias Hochgürtel , Hongbo Deng , Brian M. Gallagher, Jr. , Irving Sucholeiki , Arthur Taveras
- Applicant Address: US CA Thousand Oaks
- Assignee: Alantos Pharmaceutical Holdings, Inc.
- Current Assignee: Alantos Pharmaceutical Holdings, Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Elsa D. Lemoine
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D413/00
Abstract:
The present invention relates generally to azatriocyclic containing pharmaceutical agents, and in particular, to azatricyclic metalloprotease inhibiting compounds. More particularly, the present invention provides a new class of azatricyclic MMP-3, MMP-8 and/or MMP-13 inhibiting compounds, that exhibit an increased potency and selectivity in relation to currently known MMP-13, MMP-8 and MMP-3 inhibitors.
Public/Granted literature
- US20080207607A1 Heterotricyclic metalloprotease inhibitors Public/Granted day:2008-08-28
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