Invention Grant
US07750019B2 Pyrimidine compound having benzyl(pyridylmethyl)amine structure and medicament comprising the same
失效
具有苄基(吡啶基甲基)胺结构的嘧啶化合物及其组合物
- Patent Title: Pyrimidine compound having benzyl(pyridylmethyl)amine structure and medicament comprising the same
- Patent Title (中): 具有苄基(吡啶基甲基)胺结构的嘧啶化合物及其组合物
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Application No.: US11835127Application Date: 2007-08-07
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Publication No.: US07750019B2Publication Date: 2010-07-06
- Inventor: Tadaaki Ohgiya , Toru Miura , Ayumu Okuda , Toshiharu Arai , Koichi Yamazaki , Taro Aoki , Katsutoshi Miyosawa , Haruki Shibata , Kimiyuki Shibuya
- Applicant: Tadaaki Ohgiya , Toru Miura , Ayumu Okuda , Toshiharu Arai , Koichi Yamazaki , Taro Aoki , Katsutoshi Miyosawa , Haruki Shibata , Kimiyuki Shibuya
- Applicant Address: JP Aichi
- Assignee: Kowa Company, Ltd.
- Current Assignee: Kowa Company, Ltd.
- Current Assignee Address: JP Aichi
- Agency: Greenblum & Bernstein, P.L.C.
- Main IPC: C07D239/42
- IPC: C07D239/42 ; A61K31/505

Abstract:
A compound represented by the following general formula (I) or a salt thereof, or a solvate thereof: (wherein R1, R2, R3, R4 and R5 are the same or different, and represent hydrogen atom, a halogen atom, a lower alkyl group etc., R6, R7 and R8 are the same or different, and represent hydrogen atom, a halogen atom, a lower alkyl group etc., R9 and R10 are the same or different, and represent hydrogen atom, a lower alkyl group, a (lower cycloalkyl)(lower alkyl) group etc., and R11 represents hydrogen atom, a halogen atom, a lower alkoxy group, a (lower alkyl)thio(lower alkoxy) group, a (lower alkyl)sulfinyl(lower alkoxy) group, a (lower alkyl)sulfonyl(lower alkoxy) group etc.), which has potent inhibitory activity on CETP.
Public/Granted literature
- US20090054474A1 Novel pyrimidine compound having benzyl(pyridylmethyl)amine structure and medicament comprising the same Public/Granted day:2009-02-26
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