Invention Grant
US07750117B2 Methods for heat-stabilizing proteins with specific binding activities
有权
具有特异结合活性的蛋白质热稳定化方法
- Patent Title: Methods for heat-stabilizing proteins with specific binding activities
- Patent Title (中): 具有特异结合活性的蛋白质热稳定化方法
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Application No.: US10777825Application Date: 2004-02-11
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Publication No.: US07750117B2Publication Date: 2010-07-06
- Inventor: Mark E. Cook , Mingder Yang , Mark R. Etzel
- Applicant: Mark E. Cook , Mingder Yang , Mark R. Etzel
- Applicant Address: US WI Madison
- Assignee: Wisconsin Alumni Research Foundation
- Current Assignee: Wisconsin Alumni Research Foundation
- Current Assignee Address: US WI Madison
- Agency: Armstrong Teasdale LLP
- Main IPC: C07K16/02
- IPC: C07K16/02

Abstract:
It is disclosed here that a protein with a heat-labile specific binding activity can be stabilized with a saccharide compound with regard to the binding activity. To heat-stabilize the protein, it is mixed with a saccharide compound in a liquid suspension and the suspension is then dried to produce a solid that contains the protein and the saccharide. The saccharide compounds that possess the protein heat-stabilization activity include monosaccharides, disaccharides, polysaccharides, alkylated monosaccharides, alkylated disaccharides, alkylated polysaccharides, monosaccharide alcohols and alkylated monosaccharide alcohols.
Public/Granted literature
- US20050175602A1 Methods for heat-stabilizing proteins with specific binding activities Public/Granted day:2005-08-11
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