Invention Grant
- Patent Title: Modulation of apolipoprotein c-III expression
- Patent Title (中): 载脂蛋白c-III表达的调节
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Application No.: US10553722Application Date: 2004-04-15
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Publication No.: US07750141B2Publication Date: 2010-07-06
- Inventor: Rosanne M. Crooke , Mark J. Graham , Kenneth W. Dobie
- Applicant: Rosanne M. Crooke , Mark J. Graham , Kenneth W. Dobie
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Isis Pharmaceuticals, Inc. Patent Dept.
- International Application: PCT/US2004/010946 WO 20040415
- International Announcement: WO2004/093783 WO 20041104
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04
Abstract:
Compounds, compositions and methods are provided for modulating the expression of apolipoprotein C-III. The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein C-III. Methods of using these compounds for modulation of apolipoprotein C-III expression and for diagnosis and treatment of disease associated with expression of apolipoprotein C-III are provided.
Public/Granted literature
- US20060264395A1 Modulation of apolipoprotein c-III expression Public/Granted day:2006-11-23
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