A method of changing driving sequence to output a charge coupled device signal, the method is applied to a scanner. The scanner has a pixel processor and a charge coupled device. A plurality of charge signals detected by the charge coupled device is sequentially output to the pixel processor according to the driving sequence. In the method of changing the driving sequence to output the charge coupled device signal, a fast driving sequence is provided. The fast driving sequence has a period equal to 1/N of the original driving sequence. According to the fast driving sequence, the charge signal is sent to the pixel processing circuit. The charge signals are sampled by the processing circuit according to a sampling sequence, and the data obtained by sampling is output.