System and method for data transfer with buffer control. According to an embodiment, the present invention provides a system for synchronized data communication. The system includes a first communication interface for receiving data and a first clock signal. For example, the first clock signal is associated with a transmitting source. The system also includes a second communication interface for transmitting data. The system further includes a processing component for separating a single data stream into multiple data streams. The system additionally includes a clock that is configured to provide a second clock signal. Also, the system includes a plurality of buffer components for providing temporary storage for data streams. For example, each of the buffer components can be characterized by a predetermined buffer size. The plurality of buffering component includes a first buffer component and a second buffer component.