Invention Grant
- Patent Title: Articles of manufacture and methods for modeling Saccharomyces cerevisiae metabolism
- Patent Title (中): 酿造酵母代谢的制造和方法
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Application No.: US10263901Application Date: 2002-10-02
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Publication No.: US07751981B2Publication Date: 2010-07-06
- Inventor: Imandokht Famili , Jochen Förster , Pengcheng Fu , Jens B. Nielsen , Bernhard O. Palsson
- Applicant: Imandokht Famili , Jochen Förster , Pengcheng Fu , Jens B. Nielsen , Bernhard O. Palsson
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: DLA Piper LLP (US)
- Main IPC: G01N33/48
- IPC: G01N33/48 ; G06G7/48
Abstract:
The invention provides an in silico model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive of a S. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silico S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention.
Public/Granted literature
- US20030228567A1 Compostions and methods for modeling Saccharomyces cerevisiae metabolism Public/Granted day:2003-12-11
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