A computer server system may include a plurality of database modules for storing user data for a plurality of users, and at least one processing module comprising a plurality of processing threads for processing jobs for users based upon respective user data. The computer server system may further include a database pool module connected between the plurality of database modules and the at least one processing module. The database pool module may be for selectively connecting the processing threads to corresponding database modules including respective user data for jobs to be processed, and determining when a database module becomes unresponsive and terminating processing thread connections to the unresponsive database module based thereon. The database pool module may also be for determining when the unresponsive database module becomes responsive and restoring processing thread connectivity thereto based thereon.